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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN3
All Species:
28.48
Human Site:
T135
Identified Species:
44.76
UniProt:
Q6P5Z2
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P5Z2
NP_037487.2
889
99421
T135
T
H
T
C
A
S
G
T
P
K
E
R
K
L
L
Chimpanzee
Pan troglodytes
XP_001159776
886
99121
T135
T
H
T
C
A
S
G
T
P
K
E
R
K
L
L
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
T248
T
H
T
C
A
S
G
T
P
K
E
R
K
L
L
Dog
Lupus familis
XP_548434
951
104664
T197
T
H
T
Y
A
N
G
T
P
K
E
R
K
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8K045
878
97863
T128
I
H
T
C
A
S
G
T
P
K
E
R
K
L
L
Rat
Rattus norvegicus
O08874
985
112050
P167
I
Q
M
Y
S
N
G
P
S
K
D
R
K
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
T235
I
Q
M
Y
A
N
G
T
P
K
E
R
K
L
V
Chicken
Gallus gallus
XP_422357
1013
114806
S193
I
Q
M
Y
S
N
G
S
S
K
D
R
K
L
L
Frog
Xenopus laevis
Q7ZX15
486
56292
Zebra Danio
Brachydanio rerio
XP_697542
940
106140
S149
I
Q
T
Y
T
N
S
S
V
K
D
R
K
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
I23
P
Q
G
K
I
H
V
I
I
E
L
K
N
R
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
F80
H
Q
G
K
A
I
G
F
S
V
F
H
S
C
V
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
E75
K
V
E
L
A
L
V
E
G
F
K
N
V
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
A113
K
Y
D
C
P
S
L
A
Q
R
I
Q
Y
M
L
Red Bread Mold
Neurospora crassa
P87253
1142
127954
S98
F
E
G
Y
G
A
P
S
P
P
P
K
E
D
V
Conservation
Percent
Protein Identity:
100
97.7
81.5
84.2
N.A.
83.2
49.9
N.A.
64.2
48.9
26.2
52.2
N.A.
28
N.A.
29.1
41.5
Protein Similarity:
100
97.8
82.9
87.6
N.A.
88.4
63.6
N.A.
72.9
63
36.6
67.6
N.A.
41.5
N.A.
43.9
58.2
P-Site Identity:
100
100
100
86.6
N.A.
93.3
33.3
N.A.
60
40
0
33.3
N.A.
0
N.A.
13.3
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
53.3
N.A.
73.3
66.6
0
60
N.A.
13.3
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
27.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
43.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
54
7
0
7
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
34
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
0
0
7
0
0
0
0
0
0
0
20
0
0
7
0
% D
% Glu:
0
7
7
0
0
0
0
7
0
7
40
0
7
0
0
% E
% Phe:
7
0
0
0
0
0
0
7
0
7
7
0
0
0
0
% F
% Gly:
0
0
20
0
7
0
60
0
7
0
0
0
0
0
0
% G
% His:
7
34
0
0
0
7
0
0
0
0
0
7
0
0
7
% H
% Ile:
34
0
0
0
7
7
0
7
7
0
7
0
0
7
0
% I
% Lys:
14
0
0
14
0
0
0
0
0
60
7
14
60
0
7
% K
% Leu:
0
0
0
7
0
7
7
0
0
0
7
0
0
54
54
% L
% Met:
0
0
20
0
0
0
0
0
0
0
0
0
0
14
0
% M
% Asn:
0
0
0
0
0
34
0
0
0
0
0
7
7
0
0
% N
% Pro:
7
0
0
0
7
0
7
7
47
7
7
0
0
0
0
% P
% Gln:
0
40
0
0
0
0
0
0
7
0
0
7
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
7
0
60
0
7
0
% R
% Ser:
0
0
0
0
14
34
7
20
20
0
0
0
7
0
0
% S
% Thr:
27
0
40
0
7
0
0
40
0
0
0
0
0
0
7
% T
% Val:
0
7
0
0
0
0
14
0
7
7
0
0
7
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
40
0
0
0
0
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _